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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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C. Antibiotic Interactions:

Tamsulosin, a medication used to treat soft tissue infections, can affect the body's ability to absorb and take in the medication, which may increase the risk of resistance. If Tamsulosin is used together, the medication may stimulate the production of antibiotic active ingredients, increasing the risk of resistance.

Diaper Imatinib, a drug used to treat certain infections, is also known to affect the body. It can increase the production of antibiotics in the medication, thereby increasing its exposure to side effects.

It is contraindicated to use Tamsulosin or its alternatives, as it can increase the risk of experiencing symptoms like dizziness or fainting, which may become severe when used with nitrates or nitroprusside type medications.

Tadalafil, a medication commonly used to treat erectile dysfunction, is an anti-impotence drug.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

posesier to take than top drugs

C. Preventative measures

Seniors should exercise caution when taking top drugs, as well as those taking specific medications, to delay potential interactions. Keyed Exercise Techniques (the Seniors app) provide several tips for preventing adverse drug-drug interactions:

1. Do not take nitrates: Taking nitrates, like Cialis or alpha-blockers, with drugs like nitrates, like Cialis, can cause a significant drop in blood pressure, leading to dizziness, fainting, or orthostatic hypotension. Avoid consuming nitrates with patients taking alpha-blockers while taking Cialis.
2. Avoid combination use: While using Cialis and nitrates, avoid using other medications that contain the same active ingredient, like as yet, like sildenafil. These combination medications can be dangerous.
3. Drink plenty of water: While using Cialis and nitrates, ensure that you drink enough water to avoid possible dizziness or fainting while taking Cialis.

Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

• If you are allergic to any of the ingredients in Cialis Together
• If you have severe heart, liver or kidney problems
• If you have blood pressure concerns
• If you have non-arteritic anterior ischemic optic neuropathy
• If you are taking riociguat
• If you have other penis-related issues (deformation or painful erections)

Also, it may not be suitable for you if you have the following:

• If you have depression
• If you are taking strong anti-seizure medicine such as isosorbide dinitrate or a atazanavir
• If you have heart problems or diabetes
• If you have bleeding problems
• If you are planning to become pregnant

What is erectile dysfunction?

Erectile dysfunction is the inability to get or keep an erection hard enough for sex. It is a very common problem, but can be taken by men but not by women.

Erectile problems can be caused by many factors, including the following:

• You. ED in itself is not it's true
• This is because these are all symptoms of an underlying health condition.
• Other things that cause your penis to get or keep an erection include:
• Sex objects you have been inside your mouth or your vagina
• You have had an allergic reaction to any of the ingredients in the medicine.
• You have circulation problems.
• You have had a heart attack or a heart problem.
• You have blood vessel problems.
• You have high blood pressure.
• You have suffered straight back or tendon damage.
• You have a deformed penis shape. If you have this condition, you may be advised to consult a doctor.
• You have ever had difficulty getting or keeping an erection
• You have a heart problem.
• You have suffered kidney problems.
• You have any stomach problems.
• You have ever had a severe headache.
• You have problems or serious skin problems such as raised peeling or flaking of the skin, a skin rash, marks orasion - redness or swelling of the skin, blisters and burns
• You have had a heart attack or a stroke.

PATIENT INFORMATION

Do not take Cialis if you are allergic to tadalafil or any of the other ingredients in Cialis.

Do not take Cialis if you are also taking other medicines containing sildenafil or tadalafil. Sildenafil and tadalafil are PDE5 inhibitors. Before taking Cialis or any of its ingredients, consult your doctor or pharmacist.

Some medicines may interact with Cialis or its ingredients.

Your doctor will discuss with you these interactions during your medical consultation. Do not stop using Cialis without talking to your doctor. Cialis may not work as well without PDE5 inhibitors.

Tell your doctor if you have heart problems, liver or kidney problems, low blood pressure, have high or low blood sugar or are at risk of low blood pressure.

Tell your doctor about all the medicines you take, especially nitrates, alpha-blockers (including doxazosin), antifungals (such as fluconazole), beta blockers (such as tamsulosin), antiretroviral medicines (such as boceprevir), antibiotics (such as ertapenem or ertapenem), drugs to treat HIV (such as saquinavir), drugs to lower cholesterol (such as fusidic acid), digoxin (Lanoxin), other blood thinners (such as metoprolol or propranolol), antifungals (such as itraconazole or ketoconazole), oral steroid use (e.g., itraconazole or rivastigmine), oral steroids (e.g., voriconazole or voriconazole carboxymethyl as well as azole antifungals such as itraconazole or ketoconazole or itraconazole or ketoconazole or itraconazole or vorazole antifungals such as ketoconazole or itraconazole or zithromerechelle).

Your doctor or pharmacist may give you a low dose of Cialis if you have liver or kidney problems and you have high blood pressure. Your doctor may adjust your dose.

Tell your doctor about all the medicines you take, especially nitrates, alpha-blockers (such as aldosterone), antifungals (such as fluconazole), beta blockers (such as tamsulosin), antiretroviral medicines (such as boceprevir), antibiotics (such as saquinav), drugs to treat HIV (such as zidovudine), drugs to lower cholesterol (such as fusidic acid), digoxin (Lanoxin), other blood thinners (such as metoprolol or propranolol), drugs to treat HIV (such as saquinav), drugs to treat HIV infection (such as boceprevir), antibiotics (such as ertapenem or ertapenem), drugs for malaria (such as chloroquine or miconazole), drugs to treat HIV (such as saquinav), drugs to lower cholesterol (such as fusidic acid), digoxin (Lanoxin), other medicines used to treat HIV (such as clopidogrel), drugs for blood pressure (such as riociguat), antibiotics (such as ertapenem or ertapenem), drugs for HIV infection (such as ketoconazole or zithromerechelle), drugs used to treat HIV infection (such as ketoconazole or tamsulosin), drugs used to treat HIV infection (such as ketoconazole or zithromerechelle), oral contraceptives (e.g., ethinyl-clarithromycin or voriconazole), oral antibiotics such as erythromycin or telithromycin, low blood pressure medicines used to treat high blood pressure (e.g.